[BOOK][B] The neuroscience of autism spectrum disorders

JD Buxbaum, PR Hof - 2012 - books.google.com
Autism is no longer considered a rare disease, and the Center for Disease Control now
estimates that upwards of 730,000 children in the US struggle with this isolating brain�…

Lessons learned from studying syndromic autism spectrum disorders

Y Sztainberg, HY Zoghbi�- Nature neuroscience, 2016 - nature.com
Syndromic autism spectrum disorders represent a group of childhood neurological
conditions, typically associated with chromosomal abnormalities or mutations in a single�…

Mutant mouse models of autism spectrum disorders

G Provenzano, G Zunino, S Genovesi…�- Disease�…, 2012 - Wiley Online Library
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental
diseases characterized by a triad of specific behavioral traits: abnormal social interactions�…

[HTML][HTML] Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders

G Pintacuda, YHH Hsu, K Tsafou, KW Li, JM Mart�n…�- Cell Genomics, 2023 - cell.com
Autism spectrum disorders (ASDs) have been linked to genes with enriched expression in
the brain, but it is unclear how these genes converge into cell-type-specific networks. We�…

Disrupted circuits in mouse models of autism spectrum disorder and intellectual disability

CEM Golden, JD Buxbaum, S De Rubeis�- Current opinion in neurobiology, 2018 - Elsevier
Highlights•Mouse models of autism and intellectual disability display circuit-level
alterations.•These deficits link genetic disruptions to behavioral phenotypes.•Phenotypes�…

Genes associated with autism spectrum disorder

X Li, H Zou, WT Brown�- Brain research bulletin, 2012 - Elsevier
Autism spectrum disorder (ASD) is a heterogeneous grouping of neurodevelopmental
disorders characterized by impairment in social interaction, verbal communication and�…

Monogenic mouse models of autism spectrum disorders: common mechanisms and missing links

SW Hulbert, YH Jiang�- Neuroscience, 2016 - Elsevier
Autism spectrum disorders (ASDs) present unique challenges in the fields of genetics and
neurobiology because of the clinical and molecular heterogeneity underlying these�…

[HTML][HTML] Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease

S Watanabe, T Kurotani, T Oga, J Noguchi…�- Nature�…, 2021 - nature.com
Autism spectrum disorder (ASD) is a multifactorial disorder with characteristic synaptic and
gene expression changes. Early intervention during childhood is thought to benefit�…

The promising trajectory of autism therapeutics discovery

JL Silverman, JN Crawley�- Drug discovery today, 2014 - Elsevier
Pharmacological interventions for neurodevelopmental disorders are increasingly tractable.
Autism is a neurodevelopmental disorder that affects approximately 1% of the population�…

[HTML][HTML] Current knowledge on the genetics of autism and propositions for future research

T Bourgeron�- Comptes rendus biologies, 2016 - Elsevier
Autism spectrum disorders (ASD) are a heterogeneous group of neuropsychiatric disorders
characterized by problems in social communication, as well as by the presence of restricted�…