[BOOK][B] The neuroscience of autism spectrum disorders
JD Buxbaum, PR Hof - 2012 - books.google.com
Autism is no longer considered a rare disease, and the Center for Disease Control now
estimates that upwards of 730,000 children in the US struggle with this isolating brain�…
estimates that upwards of 730,000 children in the US struggle with this isolating brain�…
Lessons learned from studying syndromic autism spectrum disorders
Y Sztainberg, HY Zoghbi�- Nature neuroscience, 2016 - nature.com
Syndromic autism spectrum disorders represent a group of childhood neurological
conditions, typically associated with chromosomal abnormalities or mutations in a single�…
conditions, typically associated with chromosomal abnormalities or mutations in a single�…
Mutant mouse models of autism spectrum disorders
G Provenzano, G Zunino, S Genovesi…�- Disease�…, 2012 - Wiley Online Library
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental
diseases characterized by a triad of specific behavioral traits: abnormal social interactions�…
diseases characterized by a triad of specific behavioral traits: abnormal social interactions�…
[HTML][HTML] Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders
Autism spectrum disorders (ASDs) have been linked to genes with enriched expression in
the brain, but it is unclear how these genes converge into cell-type-specific networks. We�…
the brain, but it is unclear how these genes converge into cell-type-specific networks. We�…
Disrupted circuits in mouse models of autism spectrum disorder and intellectual disability
Highlights•Mouse models of autism and intellectual disability display circuit-level
alterations.•These deficits link genetic disruptions to behavioral phenotypes.•Phenotypes�…
alterations.•These deficits link genetic disruptions to behavioral phenotypes.•Phenotypes�…
Genes associated with autism spectrum disorder
X Li, H Zou, WT Brown�- Brain research bulletin, 2012 - Elsevier
Autism spectrum disorder (ASD) is a heterogeneous grouping of neurodevelopmental
disorders characterized by impairment in social interaction, verbal communication and�…
disorders characterized by impairment in social interaction, verbal communication and�…
Monogenic mouse models of autism spectrum disorders: common mechanisms and missing links
SW Hulbert, YH Jiang�- Neuroscience, 2016 - Elsevier
Autism spectrum disorders (ASDs) present unique challenges in the fields of genetics and
neurobiology because of the clinical and molecular heterogeneity underlying these�…
neurobiology because of the clinical and molecular heterogeneity underlying these�…
[HTML][HTML] Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease
S Watanabe, T Kurotani, T Oga, J Noguchi…�- Nature�…, 2021 - nature.com
Autism spectrum disorder (ASD) is a multifactorial disorder with characteristic synaptic and
gene expression changes. Early intervention during childhood is thought to benefit�…
gene expression changes. Early intervention during childhood is thought to benefit�…
The promising trajectory of autism therapeutics discovery
JL Silverman, JN Crawley�- Drug discovery today, 2014 - Elsevier
Pharmacological interventions for neurodevelopmental disorders are increasingly tractable.
Autism is a neurodevelopmental disorder that affects approximately 1% of the population�…
Autism is a neurodevelopmental disorder that affects approximately 1% of the population�…
[HTML][HTML] Current knowledge on the genetics of autism and propositions for future research
T Bourgeron�- Comptes rendus biologies, 2016 - Elsevier
Autism spectrum disorders (ASD) are a heterogeneous group of neuropsychiatric disorders
characterized by problems in social communication, as well as by the presence of restricted�…
characterized by problems in social communication, as well as by the presence of restricted�…