[HTML][HTML] Striatal circuits as a common node for autism pathophysiology

MV Fuccillo�- Frontiers in neuroscience, 2016 - frontiersin.org
Autism spectrum disorders (ASD) are characterized by two seemingly unrelated symptom
domains—deficits in social interactions and restrictive, repetitive patterns of behavioral�…

[HTML][HTML] Genetic causes and modifiers of autism spectrum disorder

L Rylaarsdam, A Guemez-Gamboa�- Frontiers in cellular�…, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous�…

[HTML][HTML] Postsynaptic autism spectrum disorder genes and synaptic dysfunction

P Bonsi, A De Jaco, L Fasano, P Gubellini�- Neurobiology of disease, 2022 - Elsevier
This review provides an overview of the synaptic dysfunction of neuronal circuits and the
ensuing behavioral alterations caused by mutations in autism spectrum disorder (ASD)�…

[HTML][HTML] Genetic architecture of autism spectrum disorder: Lessons from large-scale genomic studies

L Choi, JY An�- Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a strong genetic
component. Recently developed genomic technologies, including microarray and next�…

[HTML][HTML] Studying autism in rodent models: reconciling endophenotypes with comorbidities

A Argyropoulos, KL Gilby…�- Frontiers in human�…, 2013 - frontiersin.org
Autism spectrum disorder (ASD) patients commonly exhibit a variety of comorbid traits
including seizures, anxiety, aggressive behavior, gastrointestinal problems, motor deficits�…

First glimpses of the neurobiology of autism spectrum disorder

SJ Sanders�- Current opinion in genetics & development, 2015 - Elsevier
Rapid progress in identifying the genes underlying autism spectrum disorder (ASD) has
provided the substrate for a first wave of analyses into the underlying neurobiology. This�…

Autism genetics–an overview

J Yin, CP Schaaf�- Prenatal diagnosis, 2017 - Wiley Online Library
Autism spectrum disorder (ASD) is a highly heritable, clinically diverse group of
neurodevelopmental disorders. Its genetic heterogeneity is remarkable, with more than 800�…

Convergence of spectrums: neuronal gene network states in autism spectrum disorder

JM Sullivan, S De Rubeis, A Schaefer�- Current opinion in neurobiology, 2019 - Elsevier
Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder characterized
by social deficits and restrictive and/or repetitive behaviors. The breadth of ASD symptoms is�…

Leveraging a translational research approach to drive diagnostic and treatment advances for autism

KJ Parker�- Molecular psychiatry, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and poorly understood neurodevelopmental
disorder. There are currently no laboratory-based diagnostic tests to detect ASD, nor are�…

The genetic landscapes of autism spectrum disorders

G Huguet, E Ey, T Bourgeron�- Annual review of genomics and�…, 2013 - annualreviews.org
The autism spectrum disorders (ASD) are characterized by impairments in social interaction
and stereotyped behaviors. For the majority of individuals with ASD, the causes of the�…