Fragile X syndrome (FXS) is the leading inherited cause of mental retardation and autism
spectrum disorders worldwide. It presents with a distinct behavioral phenotype which�…

Fragile X syndrome (FXS) is associated with a complex but relatively consistent psychiatric
phenotype. Recent research has suggested neural substrates for the behavioral�…

Fragile X syndrome is the leading inherited form of mental retardation, and second only to
Down's syndrome as a cause of mental retardation attributable to an identifiable genetic�…

Findings from genetic, neurological, biochemical, psychological and pharmacological
research are combining to revolutionize understanding of the pathogenesis of�…

Fragile X Syndrome (FXS), the most common inherited cause of intellectual disabilities, is an
X-linked dominant disorder caused by the amplification of a CGG repeat in the�…

Fragile X syndrome is caused by CGG trinucleotide repeat expansion within the fragile X
mental retardation 1 gene, when repeat number exceeds 200. The typical psychiatric profile�…

Fragile X syndrome (FXS) is the leading inherited form of intellectual disability and autism
spectrum disorder, and patients can present with severe behavioural alterations, including�…

Fragile X syndrome (FXS) is a leading cause of inherited mental retardation. In the vast
majority of cases, this X-linked disorder is due to a CGG expansion in the 5′ untranslated�…

Fragile X syndrome (FXS) occurs in less than 10% of the intellectually disabled (ID)
population. The cause of FXS is a CGG trinucleotide repeat longer than 200 CGG units�…

The fragile X mental retardation 1 gene, which codes for the fragile X mental retardation 1
protein, usually has 5 to 40 CGG repeats in the 5'untranslated promoter. The full mutation is�…