Molecular and network-level mechanisms explaining individual differences in autism spectrum disorder
The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent�…
are not well understood. Using a large neuroimaging dataset, we identified three latent�…
[HTML][HTML] Connectivity alterations in autism reflect functional idiosyncrasy
Autism spectrum disorder (ASD) is commonly understood as an alteration of brain networks,
yet case-control analyses against typically-developing controls (TD) have yielded�…
yet case-control analyses against typically-developing controls (TD) have yielded�…
[HTML][HTML] Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes
Abstract Autism Spectrum Disorder (ASD) is characterized by substantial, yet highly
heterogeneous abnormalities in functional brain connectivity. However, the origin and�…
heterogeneous abnormalities in functional brain connectivity. However, the origin and�…
Functional connectivity-based subtypes of individuals with and without autism spectrum disorder
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder,
characterized by impairments in social communication and restricted, repetitive behaviors�…
characterized by impairments in social communication and restricted, repetitive behaviors�…
The emerging clinical neuroscience of autism spectrum disorder: a review
Importance Autism spectrum disorder (ASD) is a highly prevalent disorder, and community
psychiatrists are likely to treat many individuals with ASD during their clinical practice. This�…
psychiatrists are likely to treat many individuals with ASD during their clinical practice. This�…
Genetic modules for autism
B LaFlamme�- Nature Genetics, 2015 - nature.com
Autism spectrum disorder (ASD) is genetically heterogeneous, with most ASD-associated
variants accounting for very few cases. Michael Snyder and colleagues used a systems�…
variants accounting for very few cases. Michael Snyder and colleagues used a systems�…
[HTML][HTML] Neural connectivity evidence for a categorical-dimensional hybrid model of autism spectrum disorder
Background Autism spectrum disorder (ASD) encompasses a complex manifestation of
symptoms that include deficits in social interaction and repetitive or stereotyped interests�…
symptoms that include deficits in social interaction and repetitive or stereotyped interests�…
Increased functional connectivity between subcortical and cortical resting-state networks in autism spectrum disorder
Importance Individuals with autism spectrum disorder (ASD) exhibit severe difficulties in
social interaction, motor coordination, behavioral flexibility, and atypical sensory processing�…
social interaction, motor coordination, behavioral flexibility, and atypical sensory processing�…
Alterations in connectome dynamics in autism spectrum disorder: a harmonized mega-and meta-analysis study using the autism brain imaging data exchange dataset
Background Neuroimaging studies have reported functional connectome aberrancies in
autism spectrum disorder (ASD). However, the time-varying patterns of connectome�…
autism spectrum disorder (ASD). However, the time-varying patterns of connectome�…
[HTML][HTML] Reconciling dimensional and categorical models of autism heterogeneity: a brain connectomics and behavioral study
Background Heterogeneity in autism spectrum disorder (ASD) has hindered the
development of biomarkers, thus motivating subtyping efforts. Most subtyping studies divide�…
development of biomarkers, thus motivating subtyping efforts. Most subtyping studies divide�…