Objectives: To assay if plasma antibody levels in children with autism or developmental
delays (DD) differ from those with typical development as an indicator of immune function�…

An autoimmune hypothesis has been suggested for several disorders in childhood. The aim
of the study was to clarify the role of the cerebellum in ADHD and to evaluate the possible�…

Autoimmune diseases currently affect 5–7% of the world's population; in most diseases
there are circulating autoantibodies. Brain-reactive antibodies are present in approximately�…

The major histocompatibility complex comprises a number of genes that control the function
and regulation of the immune system. One of these genes, the C4B gene, encodes a product�…

Abstract Autism Spectrum Disorders (ASD) are a group of heterogeneous
neurodevelopmental conditions presenting in early childhood with a prevalence ranging�…

BACKGROUND: Immune dysfunction has been associated with autism, yet whether
maternal immune status during pregnancy plays a causal role remains to be clarified�…

The discovery of disorders that are associated with antibodies to neuronal cell-surface
proteins has led to a paradigm shift in our understanding of CNS autoimmunity. These�…

Background One of the most consistent biological findings in autism is the elevated blood
serotonin levels. Immune abnormalities, including autoimmunity with production of brain�…

A pregnant mouse model was used to compare the effect of IgG, administered E13-E18,
from mothers of children with autistic disorder (MCAD), to controls (simple-and IgG-) on�…

Autoimmunity to the central nervous system (CNS), especially to myelin basic protein (MBP),
may play a causal role in autism, a neurodevelopmental disorder. Because many autistic�…