Serum autoantibodies to human brain, identified by ELISA and Western immunoblotting,
were evaluated in 29 children with autism spectrum disorder (22 with autistic disorder), 9�…

Although autism spectrum disorder (ASD) is diagnosed on the basis of behavioral
parameters, several studies have reported immune system abnormalities and suggest the�…

Autism spectrum disorders (ASDs) are characterized by impaired language and social skills,
often with restricted interests and stereotyped behaviors. A previous investigation of blood�…

BACKGROUND: Autism may involve an autoimmune pathogenesis. Immunotherapy may
have a role in autistic children who have brain auto-antibodies. AIM: This study aimed to�…

Autism is a heterogeneous disorder with a poorly understood biological basis. Some
children with autism harbor plasma autoantibodies that target brain proteins. Similarly, some�…

Autism is a neurodevelopmental disorder of prenatal onset that is behaviorally defined.
There is increasing evidence for systemic and neuroimmune mechanisms in children with�…

The hypothesis of an immune dysfunction in autism spectrum disorders has previously been
put forward without, however, compelling evidence of a direct relation to its etiology or�…

Autism spectrum disorders (ASD) are a group of heterogeneous, behaviorally defined
disorders characterized by disturbances in social interaction and communication, often with�…

We measured autoantibodies against nine different neuron-specific antigens and three
cross-reactive peptides in the sera of autistic subjects and healthy controls by means of�…

Autoimmunity to central nervous system may have a role in the pathogenesis of autism. A
subset of anti-ds-DNA antibodies has been recently proved to be pathogenic to the brain as�…