[HTML][HTML] A Gly98Val Mutation in the N-Myc Downstream Regulated Gene 1 (NDRG1) in Alaskan Malamutes with Polyneuropathy

CS Bruun, KH J�derlund, M Berendt, KB Jensen…�- PLoS�…, 2013 - journals.plos.org
The first cases of early-onset progressive polyneuropathy appeared in the Alaskan
Malamute population in Norway in the late 1970s. Affected dogs were of both sexes and�…

[HTML][HTML] A Deletion in the N-Myc Downstream Regulated Gene 1 (NDRG1) Gene in Greyhounds with Polyneuropathy

C Dr�gem�ller, D Becker, B Kessler, E Kemter…�- PLoS�…, 2010 - journals.plos.org
The polyneuropathy of juvenile Greyhound show dogs shows clinical similarities to the
genetically heterogeneous Charcot-Marie-Tooth (CMT) disease in humans. The pedigrees�…

Expression analysis of the N-Myc downstream-regulated gene 1 indicates that myelinating Schwann cells are the primary disease target in hereditary motor and�…

P Berger, EE Sirkowski, SS Scherer, U Suter�- Neurobiology of disease, 2004 - Elsevier
Mutations in the gene encoding N-myc downstream-regulated gene-1 (NDRG1) lead to
truncations of the encoded protein and are associated with an autosomal recessive�…

[HTML][HTML] N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy–Lom

L Kalaydjieva, D Gresham, R Gooding…�- The American Journal of�…, 2000 - cell.com
Hereditary motor and sensory neuropathies, to which Charcot-Marie-Tooth (CMT) disease
belongs, are a common cause of disability in adulthood. Growing awareness that axonal�…

NDRG1 interacts with APO AI and A-II and is a functional candidate for the HDL-C QTL on 8q24

M Hunter, D Angelicheva, I Tournev, E Ingley…�- Biochemical and�…, 2005 - Elsevier
Hereditary Motor and Sensory Neuropathy Lom (HMSNL) is a severe autosomal recessive
peripheral neuropathy, the most common form of demyelinating Charcot-Marie-Tooth (CMT)�…

Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family

X Qu, Y Zhai, H Wei, C Zhang, G Xing, Y Yu…�- Molecular and cellular�…, 2002 - Springer
NDRG1 (N-Myc downstream regulated) is upregulated during cell differentiation, repressed
by N-myc and c-myc in embryonic cells, and suppressed in several tumor cells. A nonsense�…

N‐myc downstream‐regulated gene 1 expression in injured sciatic nerves

K Hirata, K Masuda, W Morikawa, JW He, A Kuraoka…�- Glia, 2004 - Wiley Online Library
N‐myc downstream‐regulated gene 1 (NDRG1)/RTP/Drg1/Cap43/rit42/TDD5/Ndr1 is
expressed ubiquitously and has been proposed to play a role in growth arrest and cell�…

Differential expression patterns of NDRG family proteins in the central nervous system

T Okuda, K Kokame, T Miyata�- Journal of Histochemistry &�…, 2008 - journals.sagepub.com
The N-myc downstream-regulated gene (NDRG) family consists of four proteins: NDRG1,
NDRG2, NDRG3, and NDRG4 in mammals. NDRG1 has been thoroughly studied as an�…

[HTML][HTML] NDRG4 protein-deficient mice exhibit spatial learning deficits and vulnerabilities to cerebral ischemia

H Yamamoto, K Kokame, T Okuda, Y Nakajo…�- Journal of Biological�…, 2011 - ASBMB
The N-myc downstream-regulated gene (NDRG) family consists of four related proteins,
NDRG1-NDRG4, in mammals. We previously generated NDRG1-deficient mice that were�…

Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice

X Qu, J Li, HS Baldwin�- Biochemical and biophysical research�…, 2016 - Elsevier
NDRG4 is a member of the NDRG family (N-myc downstream-regulated gene), which is
highly expressed in brain and heart. Previous studies showed that Ndrg1-deficient mice�…