There have been dramatic advances in gastrointestinal sciences over the past 10 years
since the inauguration of the Frontiers in Gastrointestinal Sciences. In 2010, I suggested that�…

The healthy human gut is a balanced ecosystem where host cells and representatives of the
gut microbiota interact and communicate in a bidirectional manner at the gut epithelium. As�…

The field of the gut microbiota is still a relatively young science area, yet many studies have
already highlighted the translational potential of microbiome research in the context of�…

The digestive system is directly related to physical health. The American Gastroenterological
Association defines good digestive health as a digestive system that fits key features�…

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis Page 1 Correction
Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis Sebastiaan De�…

Epithelial cells, stromal cells, immune cells, and microbiota are fundamental components of
the intestine, and all are importantin maintaining a healthy gut (1). Risk factors that�…

It has been well acknowledged that the gut microbiota (GM), the collection mainly of bacteria
that symbiotically inhabit the gut, acts as an “invisible organ” exerting profound impacts on�…

1 Epigenetics and Epigenome Research Institute, Yangzhou University, Yangzhou, China, 2
Department of General Surgery, Jinling Hospital, School of Medicine, Nanjing University�…

Many chronic conditions are associated with gut dysbiosis and systemic inflammation.
Identifying whether the gut barrier is compromised in these conditions could help to inform�…