[HTML][HTML] Mettl3-dependent m6A modification attenuates the brain stress response in Drosophila
Abstract N 6-methyladenosine (m6A), the most prevalent internal modification on eukaryotic
mRNA, plays an essential role in various stress responses. The brain is uniquely vulnerable�…
mRNA, plays an essential role in various stress responses. The brain is uniquely vulnerable�…
Dynamic m6A methylation facilitates mRNA triaging to stress granules
M Anders, I Chelysheva, I Goebel…�- Life science�…, 2018 - life-science-alliance.org
Reversible post-transcriptional modifications on messenger RNA emerge as prevalent
phenomena in RNA metabolism. The most abundant among them is N6-methyladenosine�…
phenomena in RNA metabolism. The most abundant among them is N6-methyladenosine�…
[HTML][HTML] The role of m6A/m-RNA methylation in stress response regulation
Summary N 6-methyladenosine (m 6 A) and N 6, 2′-O-dimethyladenosine (m 6 Am) are
abundant mRNA modifications that regulate transcript processing and translation. The role�…
abundant mRNA modifications that regulate transcript processing and translation. The role�…
[HTML][HTML] The m6A epitranscriptome on neural development and degeneration
YP Yen, JA Chen�- Journal of biomedical science, 2021 - Springer
Abstract N 6-methyladenosine (m 6 A) is the most prevalent, conserved, and abundant RNA
modification of the mRNAs of most eukaryotes, including mammals. Similar to epigenetic�…
modification of the mRNAs of most eukaryotes, including mammals. Similar to epigenetic�…
[HTML][HTML] A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
Epitranscriptomic modifications can impact behavior. Here, we used Drosophila
melanogaster to study N6-methyladenosine (m6A), the most abundant modification of�…
melanogaster to study N6-methyladenosine (m6A), the most abundant modification of�…
[HTML][HTML] N6-methyladenosine dynamics in neurodevelopment and aging, and its potential role in Alzheimer's disease
Abstract Background N6-methyladenosine (m 6 A) modification is known to impact many
aspects of RNA metabolism, including mRNA stability and translation, and is highly�…
aspects of RNA metabolism, including mRNA stability and translation, and is highly�…
[HTML][HTML] RNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum
C Ma, M Chang, H Lv, ZW Zhang, W Zhang, X He…�- Genome biology, 2018 - Springer
Abstract Background N 6-methyladenosine (m 6 A) is an important epitranscriptomic mark
with high abundance in the brain. Recently, it has been found to be involved in the�…
with high abundance in the brain. Recently, it has been found to be involved in the�…
[HTML][HTML] Emerging roles of N6-methyladenosine modification in neurodevelopment and neurodegeneration
L Shu, X Huang, X Cheng, X Li�- Cells, 2021 - mdpi.com
N6-methyladenosine (m6A), the most abundant modification in messenger RNAs (mRNAs),
is deposited by methyltransferases (“writers”) Mettl3 and Mettl14 and erased by�…
is deposited by methyltransferases (“writers”) Mettl3 and Mettl14 and erased by�…
Dynamic m6A mRNA methylation directs translational control of heat shock response
The most abundant mRNA post-transcriptional modification is N 6-methyladenosine (m6A),
which has broad roles in RNA biology,,,,. In mammalian cells, the asymmetric distribution of�…
which has broad roles in RNA biology,,,,. In mammalian cells, the asymmetric distribution of�…
[HTML][HTML] Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington's disease mice
A Pupak, A Singh, A Sancho-Balsells…�- Cellular and Molecular�…, 2022 - Springer
Abstract N6-methyladenosine (m6A) regulates many aspects of RNA metabolism and is
involved in learning and memory processes. Yet, the impact of a dysregulation of post�…
involved in learning and memory processes. Yet, the impact of a dysregulation of post�…