Studies of neuromodulation of spatial short-term memory have shown that dopamine D1
receptor (D1R) stimulation in dorsolateral prefrontal cortex (DLPFC) dose-dependently�…

The neurotransmitter dopamine, which acts via the D1-like receptor (D1R) and D2-like
receptor (D2R) family, may play an important role in gating sensory information to the�…

Abstract Dopamine (DA) D1 receptor (D1R) stimulation in prefrontal cortex (PFC) produces
an'inverted-U'dose-response, whereby either too little or too much D1R stimulation impairs�…

Recent studies on the neurobiology of cognition have focused on the ability of the prefrontal
cortex (PFC) to support processes of working memory, ie, mnemonic processes by which�…

Prefrontal neurons engaged by working memory tasks express a sequence of phasic and
tonic activations linked to a train of sensory, mnemonic, and response-related events. Here�…

1. To examine the role of dopamine receptors in the prefrontal cortex (PFC) on working
memory, we injected dopamine antagonists (SCH23390, SCH39166, haloperidol, sulpiride�…

Like the striatum, the frontal motor cortices receive dopaminergic fibers from midbrain
dopamine cells and contain high levels of dopamine receptors. Among frontal cortical areas�…

To examine the role of dopamine receptors in the memory field of neurons for visuospatial
working memory in the prefrontal cortex (PFC), dopamine and its antagonists (SCH23390 for�…

Temporal control, or how organisms guide movements in time to achieve behavioral goals,
depends on dopamine signaling. The medial prefrontal cortex controls many goal-directed�…

Dopaminergic modulation of prefrontal cortex plays an important role in numerous cognitive
processes, including attention. The frontal eye field (FEF) is modulated by dopamine and�…