The male predominance of Autism Spectrum Disorders (ASD) is one of the best-known, and
at the same time, one of the least understood characteristics of these disorders. In this paper�…

Abstract Purpose of Review Neurodevelopmental disorders disproportionately affect males.
The mechanisms underlying male vulnerability or female protection are not known and�…

Autism Spectrum Conditions (ASC) are much more common in males, a bias that may offer
clues to the etiology of this condition. Although the cause of this bias remains a mystery, we�…

Sex differences in autism spectrum disorders : Current Opinion in Neurology Sex differences in
autism spectrum disorders : Current Opinion in Neurology Log in or Register Subscribe to�…

We offer a neurobiologic theory based on animal work that helps account for the
conspicuous male predominance in autism spectrum disorders (ASD). In young male�…

Males are at least four times more likely to develop autism than females. Among relatives
with a broader autistic phenotype, males predominate too. Autism is a highly heritable�…

Autism spectrum disorder (ASD) is a developmental condition that affects approximately four
times as many males as females, a strong sex bias that has not yet been fully explained�…

Autism has long been described as a predominantly male condition, with a widely cited
male: female ratio of 4 to 5: 1 [1]. Over the past two decades, we have witnessed a trend�…

Despite the identification of numerous autism susceptibility genes, the pathobiology of
autism remains unknown. The present “case-control” study takes a global approach to�…

Experiments in animals leave no doubt that androgens, including testosterone, produced by
the testes in fetal and/or neonatal life act on the brain to induce sex differences in neural�…