… -like guanine nucleotide exchange factor (GEF) in Drosophila, called GEFmeso, as a novel
binding target of the Ras-like GTPase Ral. Previous studies suggested that some aspects of …

… , Rac1 and RhoA with GEFmeso, a GEF expressed in Drosophila melanogaster (… Our results
suggest that GEFmeso interacts with Rac1 in addition to its interaction with CDC42 and Ral, …

… and nucleotide depleted Cdc42 in vitro, suggesting GEFmeso is an exchange factor for Cdc42
and an … and Egfr, I show that GEFmeso interacts with Ras in four wing microdomains. One …

… activation of the Drosophila melanogaster orthologue of RhoA… the pathogenesis of HD include
Cdc42-interacting protein 4 (… pathways to increase and reveal novel targets for therapeutic …

… However, the mechanism of this interaction is poorly … GEFmeso is a guanine nucleotide
exchange factor identified … This assay offers an excellent opportunity to determine where novel …

… interacting-protein 1 (Tip-1) and we now report identification and functional analysis of a novel
… This has identified the guanine nucleotide exchange factor 16 (ARHGEF16; subsequently …

… RAL GTPases are necessary and sufficient to activate EGFR/MAPK signalling in the intestine,
via induction of EGFR internalisation. Knocking down Drosophila … of RAL GTPases impacts …

… of the Rac-specific guanine nucleotide exchange factors, Tiam1 and Trio, … novel in that they
are the first to reveal the temporal and cell type-specific dysregulation of Rho family GTPases …

… We had shown earlier that interaction of the HPV16 E6 … guanidine exchange factor ARHGEF16
(GEF16) as a novel binding … a potential Cdc42-binding motif (Blanke and Jackle, 2006) …

… RNA interactions mediated by Sec-specific elongation factors… and invertebrates such as
Drosophila melanogaster (15… Here we report on a novel component of the Drosophila UGA …