[HTML][HTML] Activity-dependent proteolytic cleavage of neuroligin-1

K Suzuki, Y Hayashi, S Nakahara, H Kumazaki, J Prox…�- Neuron, 2012 - cell.com
… Collectively, neuronal activity-dependent proteolytic processing of … cleaved by ADAM10
and γ-secretase to release its extra- and intracellular domain fragments, respectively. Proteolytic

[CITATION][C] Activity-dependent proteolytic cleavage of Neuroligin-1

鈴木邦道, 林ゆかり, 中原総一朗�- 細胞科学研究財団助成研究報告集�…, 2013 - cir.nii.ac.jp
Activity-dependent proteolytic cleavage of Neuroligin-1 | CiNii Research … Activity-dependent
proteolytic cleavage of Neuroligin-1 … シナプス接着分子Neuroligin-1の神経活動依存的な�…

Activity-dependent proteolytic cleavage of cell adhesion molecules regulates excitatory synaptic development and function

S Nagappan-Chettiar, EM Johnson-Venkatesh…�- Neuroscience�…, 2017 - Elsevier
… ., 2010, Peixoto et al., 2012). In this review, we will discuss the role of … Neuroligin-1 cleavage
still requires elucidation, we speculate that the activity-dependent cleavage of Neuroligin-1

[HTML][HTML] Functional significance of rare neuroligin 1 variants found in autism

M Nakanishi, J Nomura, X Ji, K Tamada, T Arai…�- PLoS�…, 2017 - journals.plos.org
… leads to excessive cleavage of NLGN1, which was concomitant with decreased NLGN1
expression. This cleavage process may be linked to the activity-dependent degradation of …

Activity-dependent synaptic recruitment of neuroligin 1 in spinal dorsal horn contributed to inflammatory pain

JY Zhao, XL Duan, L Yang, JP Liu, YT He, Z Guo…�- Neuroscience, 2018 - Elsevier
… of NLGN1, we observed the cleavage of NLGN1 in spinal cord of intact mice and inflamed
mice. However, the significance of proteolytic cleavage in inflammatory pain remained to be …

Tuning synapses by proteolytic remodeling of the adhesive surface

T Shinoe, Y Goda�- Current Opinion in Neurobiology, 2015 - Elsevier
neuroligin-1 as one of the substrates of MMP-9 (Figure 3a–c) [48 •• ]. MMP-9-dependent
cleavage of neuroligin-1 … are related to activity-dependent metalloprotease cleavage of N-…

[HTML][HTML] Neuroligin 1, 2, and 3 regulation at the synapse: FMRP-dependent translation and activity-induced proteolytic cleavage

JJ Chmielewska, B Kuzniewska, J Milek…�- Molecular�…, 2019 - Springer
… Male P30-40 WT and Fmr1 KO mice were used to show activity-dependent NLGNs
cleavage in Fig. 7a–c, while male P40 WT and Nlgn3 KO mice were used in Fig. 7g. …

Posttranslational modifications of neuroligins regulate neuronal and glial signaling

J Jeong, JD Paskus, KW Roche�- Current Opinion in Neurobiology, 2017 - Elsevier
… studies describe activity-dependent proteolytic cleavage of … Interesting new research implicates
the cleaved extracellular … inhibited the extracellular cleavage in both studies, Suzuki et al. …

Proteolytic cleavage is required for functional neuroligin 2 maturation and trafficking in Drosophila

R Tu, J Qian, M Rui, N Tao, M Sun…�- Journal of Molecular�…, 2017 - academic.oup.com
… where, in contrast to the activity-dependent cleavage of Nlg1 on the synapse in rodents, the
… People started to realize the cleavage modification to Nlgs from the year 2012, and only …

Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma

HS Venkatesh, LT Tam, PJ Woo, J Lennon, S Nagaraja…�- Nature, 2017 - nature.com
… An important mechanism that mediates this neural regulation of brain cancer is activity-dependent
cleavage and secretion of the synaptic adhesion molecule neuroligin-3 (NLGN3), …