A disinhibitory circuit motif and flexible information routing in the brain

XJ Wang, GR Yang�- Current opinion in neurobiology, 2018 - Elsevier
disinhibitory motif. Then, we will discuss requirements and supporting evidence for this circuit
motif to … operation and flexible functions of the cell-type specific large-scale brain systems. …

Macroscopic gradients of synaptic excitation and inhibition in the neocortex

XJ Wang�- Nature reviews neuroscience, 2020 - nature.com
… , the neuroscience of brain-wide neural circuits is poised to … its output is sent to the thalamus
en route to V1, the output of … In a disinhibitory motif initially proposed theoretically 82 and …

Theory of the multiregional neocortex: large-scale neural dynamics and distributed cognition

XJ Wang�- Annual review of neuroscience, 2022 - annualreviews.org
… How these regions work together to subserve flexible … the distribution of triad motifs (graphs
made of three areas). … beyond local circuits toward a neuroscience of the whole brain. In …

50 years of mnemonic persistent activity: quo vadis?

XJ Wang�- Trends in Neurosciences, 2021 - cell.com
… ability of the brain to hold and manipulate information when sensory stimulation is absent [
… of the brain. A working memory system is in turn conceptualized as a neural circuit endowed …

[HTML][HTML] Coordination of escape and spatial navigation circuits orchestrates versatile flight from threats

W Wang, PJ Schuette, J Nagai, BC Tobias, FMCV Reis…�- Neuron, 2021 - cell.com
… how spatial navigation is integrated with escape to produce context-specific escape
requiring flexible decision-making to identify efficient flight routes in complex environments. …

Flexible control of representational dynamics in a disinhibition-based model of decision-making

B Shen, K Louie, P Glimcher�- Elife, 2023 - elifesciences.org
… Here, we show that disinhibition provides a simple circuit motif2018), how disinhibition
functions in decision- making … nor predict contextual choice patterns (Wang, 2012) due to the lack …

[HTML][HTML] Thalamocortical circuit motifs: a general framework

MM Halassa, SM Sherman�- Neuron, 2019 - cell.com
… that a proper classification of motifs underlying these interactions is … , as well as development
of brain-inspired artificial neural … to the thalamic reticular nucleus en route to the cortex), …

Hierarchical timescales in the neocortex: Mathematical mechanism and biological insights

S Li, XJ Wang�- Proceedings of the National Academy of�…, 2022 - National Acad Sciences
… The brain is organized with a delicate structure to integrate and process both spatial and …
by strongly recurrent circuit dynamics to enhance signal propagation or routing of information is …

[HTML][HTML] Neural circuit motifs in valence processing

KM Tye�- Neuron, 2018 - cell.com
… How do our brains determine whether something is good or … for survival, the brain has
evolved multiple strategies to solve … of studies that exemplify circuit motifs that repeatedly appear …

[HTML][HTML] Thalamic regulation of frontal interactions in human cognitive flexibility

A Hummos, BA Wang, S Drammis…�- PLoS Computational�…, 2022 - journals.plos.org
… The model predicted an efficient route through the MD for … of thalamic nuclei in the human
brain are suspected, evidence … of OFC in the network switching motif (dlPFC, OFC and MD), …