[HTML][HTML] Cortical patterning of morphometric similarity gradient reveals diverged hierarchical organization in sensory-motor cortices

S Yang, K Wagstyl, Y Meng, X Zhao, J Li, P Zhong, B Li…�- Cell Reports, 2021 - cell.com
The topological organization of the cerebral cortex provides hierarchical axes, namely
gradients, which reveal systematic variations of brain structure and function. However, the�…

[HTML][HTML] Morphometric brain organization across the human lifespan reveals increased dispersion linked to cognitive performance

J Li, C Zhang, Y Meng, S Yang, J Xia, H Chen…�- Plos Biology, 2024 - journals.plos.org
The human brain is organized as segregation and integration units and follows complex
developmental trajectories throughout life. The cortical manifold provides a new means of�…

[HTML][HTML] Transcriptional cartography integrates multiscale biology of the human cortex

K Wagstyl, S Adler, J Seidlitz, S Vandekar, TT Mallard…�- Elife, 2024 - elifesciences.org
The cerebral cortex underlies many of our unique strengths and vulnerabilities, but efforts to
understand human cortical organization are challenged by reliance on incompatible�…

Multi-centre analysis of networks and genes modulated by hypothalamic stimulation in patients with aggressive behaviours

FV Gouveia, J Germann, GJB Elias, A Boutet, A Loh…�- Elife, 2023 - elifesciences.org
Deep brain stimulation targeting the posterior hypothalamus (pHyp-DBS) is being
investigated as a treatment for refractory aggressive behavior, but its mechanisms of action�…

[HTML][HTML] Pervasive alterations of intra-axonal volume and network organization in young children with a 16p11. 2 deletion

AM Maillard, D Romascano, JE Villal�n-Reina…�- Translational�…, 2024 - nature.com
Abstract Reciprocal Copy Number Variants (CNVs) at the 16p11. 2 locus confer high risk for
autism spectrum disorder (ASD) and other neurodevelopmental disorders (NDDs)�…

High spatial overlap but diverging age‐related trajectories of cortical magnetic resonance imaging markers aiming to represent intracortical myelin and microstructure

O Parent, E Olafson, A Bussy, S Tullo…�- Human brain�…, 2023 - Wiley Online Library
Statistical effects of cortical metrics derived from standard T1‐and T2‐weighted magnetic
resonance imaging (MRI) images, such as gray–white matter contrast (GWC), boundary�…

[HTML][HTML] Cortical remodelling in childhood is associated with genes enriched for neurodevelopmental disorders

G Ball, J Seidlitz, R Beare, ML Seal�- Neuroimage, 2020 - Elsevier
Cortical development during childhood and adolescence has been characterised in recent
years using metrics derived from Magnetic Resonance Imaging (MRI). Changes in cortical�…

Transcriptomic and macroscopic architectures of multimodal covariance network reveal molecular–structural–functional co-alterations

L Jiang, Y Peng, R He, Q Yang, C Yi, Y Li, B Zhu, Y Si…�- Research, 2023 - spj.science.org
Human cognition is usually underpinned by intrinsic structure and functional neural co-
activation in spatially distributed brain regions. Owing to lacking an effective approach to�…

[HTML][HTML] Spatial and temporal pattern of structure–function coupling of human brain connectome with development

G Feng, Y Wang, W Huang, H Chen, J Cheng, N Shu�- eLife, 2024 - elifesciences.org
Brain structural circuitry shapes a richly patterned functional synchronization, supporting for
complex cognitive and behavioural abilities. However, how coupling of structural�…

Cortical morphometric vulnerability to generalised epilepsy reflects chromosome‐and cell type‐specific transcriptomic signatures

J Li, SS Keller, J Seidlitz, H Chen, B Li…�- Neuropathology and�…, 2023 - Wiley Online Library
Aims Generalised epilepsy is thought to involve distributed brain networks. However, the
molecular and cellular factors that render different brain regions more vulnerable to�…