Itch is a protective/defensive function with divalent motivational drives. Itch itself elicits an
unpleasant experience, which triggers the urge to scratch, relieving the itchiness. Still, it can�…

Itch is an unpleasant sensation that initiates scratching behavior. The itch–scratch reaction is
a complex phenomenon that implicates supraspinal structures required for regulation of�…

Itch is an unpleasant sensation that provokes the desire to scratch. While acute itch serves
as a protective system to warn the body of external irritating agents, chronic itch is a�…

Itch is a complex and unpleasant sensory experience. Recent studies have begun to
investigate the neural mechanisms underlying the modulation of sensory and emotional�…

Itch is a distinctive sensation that causes a specific affection and scratching reaction. The
anterior cingulate cortex (ACC) has been linked to itch sensation in numerous studies;�…

Itch is an unpleasant sensation that evokes a desire to scratch. Itch processing in the
peripheral and spinal cord has been studied extensively, but the mechanism of itch in the�…

Ventral tegmental area (VTA) dopaminergic neurons, which are well known for their central
roles in reward and motivation-related behaviors, have been shown to participate in itch�…

Itch is an uncomfortable and complex sensation that elicits the desire to scratch. The nucleus
accumbens (NAc) activity is important in driving sensation, motivation, and emotion�…

Itch is an unpleasant sensation that induces the desire to scratch. Except for a sketchy map
focusing on neural mechanisms underlying itch processing being drawn at the peripheral�…

The itch-scratching cycle is mediated by neural dynamics in the brain. However, our
understanding of the neural dynamics during this cycle remains limited. In this study, we�…