[HTML][HTML] Morphometric brain organization across the human lifespan reveals increased dispersion linked to cognitive performance
The human brain is organized as segregation and integration units and follows complex
developmental trajectories throughout life. The cortical manifold provides a new means of�…
developmental trajectories throughout life. The cortical manifold provides a new means of�…
[HTML][HTML] Pervasive alterations of intra-axonal volume and network organization in young children with a 16p11. 2 deletion
AM Maillard, D Romascano, JE Villal�n-Reina…�- Translational�…, 2024 - nature.com
Abstract Reciprocal Copy Number Variants (CNVs) at the 16p11. 2 locus confer high risk for
autism spectrum disorder (ASD) and other neurodevelopmental disorders (NDDs)�…
autism spectrum disorder (ASD) and other neurodevelopmental disorders (NDDs)�…
Morphological and genetic decoding shows heterogeneous patterns of brain aging in chronic musculoskeletal pain
Chronic musculoskeletal pain (CMP), a prevalent and heterogeneous condition
characterized by persistent pain in various body parts, is a leading cause of disability�…
characterized by persistent pain in various body parts, is a leading cause of disability�…
[HTML][HTML] Integrative omics analysis reveals epigenomic and transcriptomic signatures underlying brain structural deficits in major depressive disorder
Several lines of evidence support the involvement of transcriptomic and epigenetic
mechanisms in the brain structural deficits of major depressive disorder (MDD) separately�…
mechanisms in the brain structural deficits of major depressive disorder (MDD) separately�…
[HTML][HTML] Spatial and temporal pattern of structure–function coupling of human brain connectome with development
Brain structural circuitry shapes a richly patterned functional synchronization, supporting for
complex cognitive and behavioural abilities. However, how coupling of structural�…
complex cognitive and behavioural abilities. However, how coupling of structural�…
[HTML][HTML] Epigenetic profile of the immune system associated with symptom severity and treatment response in schizophrenia
Y Tang, Y Tan, L Palaniyappan, Y Yao, Q Luo…�- Journal of Psychiatry and�…, 2024 - jpn.ca
Background: Environmental modification of genetic information (epigenetics) is often
invoked to explain interindividual differences in the phenotype of schizophrenia. In clinical�…
invoked to explain interindividual differences in the phenotype of schizophrenia. In clinical�…
Characterizing the distinct imaging phenotypes, clinical behavior, and genetic vulnerability of brain maturational subtypes in mood disorders
BackgroundMood disorders are characterized by great heterogeneity in clinical
manifestation. Uncovering such heterogeneity using neuroimaging-based individual�…
manifestation. Uncovering such heterogeneity using neuroimaging-based individual�…
[HTML][HTML] Transcriptional cartography integrates multiscale biology of the human cortex
The cerebral cortex underlies many of our unique strengths and vulnerabilities, but efforts to
understand human cortical organization are challenged by reliance on incompatible�…
understand human cortical organization are challenged by reliance on incompatible�…
How Do Neurotransmitter Pathways Contribute to Neuroimaging Phenotypes?
Neuroimaging could accurately reflect human behaviour in health and disease, but the
mechanism by which image-derived phenotypes correspond to neurotransmitter systems�…
mechanism by which image-derived phenotypes correspond to neurotransmitter systems�…
[HTML][HTML] Unraveling the molecular relevance of brain phenotypes: A comparative analysis of null models and test statistics
Correlating transcriptional profiles with imaging-derived phenotypes has the potential to
reveal possible molecular architectures associated with cognitive functions, brain�…
reveal possible molecular architectures associated with cognitive functions, brain�…