[HTML][HTML] Preservation of thalamic neuronal function may be a prerequisite for pain perception in diabetic neuropathy: a magnetic resonance spectroscopy study

R Gandhi, D Selvarajah, G Sloan, M Greig…�- Frontiers in Pain�…, 2023 - frontiersin.org
mechanism of thalamic neuronal dysfunction in painless-DPN … thalamic hyperperfusion in
painful- compared with painless-… in DPN, thalamic NAA:Cr was reduced in painless- but not

Structural brain alterations in key somatosensory and nociceptive regions in diabetic peripheral neuropathy

D Selvarajah, G Sloan, K Teh, ID Wilkinson…�- Diabetes�…, 2023 - Am Diabetes Assoc
… and ventrobasal thalamic nuclei volume in both the painful and painless DPN cohorts was
Diabetic Neuropathy (COMBO-DN) study showed that optimizing neuropathic pain treatment

Central Nervous System Involvement in Painful Diabetic Neuropathy

D Selvarajah, J Lim, K Teh, X Chen, J Wu…�- …�in Pathophysiology and�…, 2023 - Springer
… in thalamic grey matter volume in subjects with painlessclues to why some patients respond,
whilst others are non-… As in other microvascular complications for diabetes, eg diabetic

Pathophysiology of Neuropathic Pain

AC Themistocleous, MM Backonja�- …�: Advances in Pathophysiology and�…, 2023 - Springer
… between painless and painful diabetic neuropathy, found … microvascular vasodilator and
vasoconstrictor responses are … in the thalamus of only those with painful diabetic neuropathy [73]…

Alterations in functional connectivity of thalamus and primary somatosensory cortex in painful and painless diabetic peripheral neuropathy

SS Croosu, J R�ikjer, CD M�rch, N Ejskjaer…�- Diabetes�…, 2023 - Am Diabetes Assoc
… Unfortunately, early diagnosis and proper treatment of … with painless and painful DPN
demonstrated further abnormalpainless DPN had DPN but no pain and that the group with …

Increased thalamocortical functional connectivity on discontinuation of treatment in painful diabetic peripheral neuropathy

G Sloan, K Teh, S Caunt, I Wilkinson, D Selvarajah…�- Diabetes, 2024 - diabetesjournals.org
Microvascular perfusion abnormalities of the Thalamus in painful but not painless
diabetic polyneuropathy: a clue to the pathogenesis of pain in type 1 diabetes. …

Higher sensory cortical energy metabolism in painful diabetic neuropathy: evidence from a cerebral magnetic resonance spectroscopy study

G Sloan, A Anton, S Caunt, I Wilkinson, D Selvarajah…�- Diabetes, 2023 - Am Diabetes Assoc
pathophysiology of painfulpain processing areas in patients with the painful insensate
phenotype. Moreover, there is a reduction in thalamic neuronal function in patients with painless

Diabetic neuropathy

S Tesfaye, T Didangelos�- The Diabetic Foot: Medical and Surgical�…, 2024 - Springer
… entities and perhaps providing clues to the varied aetiologies… severe microvascular changes
in subjects with acute painful … (NAA:Cr) ratio in the thalamus and white matter tracts of the …

Reduced Thalamic Gamma Aminobutyric Acid (GABA) in Painless but not Painful Diabetic Peripheral Neuropathy

P Shillo, G Sloan, D Selvarajah, M Greig, R Gandhi…�- Diabetes, 2024 - Am Diabetes Assoc
Microvascular perfusion abnormalities of the Thalamus in painful but not painless
diabetic polyneuropathy: a clue to the … Diabetes Care 2011;34:718-720 6. Gandhi R, …

Efficacy and safety of acupuncture for painful diabetic neuropathy: a systematic review and meta-analysis

J Liu, Y Lin, Y Huang, Q Yang, X Li, Y Ye…�- Frontiers in�…, 2024 - frontiersin.org
… Medications are often used to relieve pain, but with … , elevated blood pressure, abnormal
cardiac arrhythmias, and … density in early neuropathy (56), increased thalamic vascularity (57), …