[HTML][HTML] RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis
M N�szai, K Bellec, Y Yu, A Rom�n-Fern�ndez…�- Elife, 2021 - elifesciences.org
… RAL GTPases are necessary and sufficient to activate EGFR/MAPK signalling in the intestine,
via induction of EGFR internalisation. Knocking down Drosophila … of RAL GTPases impacts …
via induction of EGFR internalisation. Knocking down Drosophila … of RAL GTPases impacts …
[HTML][HTML] Dysregulation of Rac or Rho elicits death of motor neurons and activation of these GTPases is altered in the G93A mutant hSOD1 mouse model of�…
TR Stankiewicz, C Pena, RJ Bouchard…�- Neurobiology of�…, 2020 - Elsevier
… of the Rac-specific guanine nucleotide exchange factors, Tiam1 and Trio, … novel in that they
are the first to reveal the temporal and cell type-specific dysregulation of Rho family GTPases …
are the first to reveal the temporal and cell type-specific dysregulation of Rho family GTPases …
[PDF][PDF] RAL GTPases mediate EGFR/MAPK signalling-driven intestinal stem cell proliferation and tumourigenesis upstream of RAS activation
M Naszai, Y Yu, AR Fernandez, E Sandilands…�- BioRxiv, 2020 - researchgate.net
… Whether RAL proteins work as canonical … RAL GTPases are necessary and sufficient to
activate EGFR/MAPK signalling in the intestine. We identify noncanonical roles of RAL GTPases, …
activate EGFR/MAPK signalling in the intestine. We identify noncanonical roles of RAL GTPases, …
RAL GTPases mediate EGFR-driven intestinal stem cell hyperproliferation and tumourigenesis
M N�szai, K Bellec, Y Yu, � Rom�n-Fern�ndez…�- bioRxiv, 2020 - biorxiv.org
… We recently identified a novel role of RAL GTPases in the … Quantification of pH3 positive
nuclei in control or GEFmeso-… During our initial assessment of genetic interactions between …
nuclei in control or GEFmeso-… During our initial assessment of genetic interactions between …