… , the neuroscience of brain-wide neural circuits is poised to … its output is sent to the thalamus
en route to V1, the output of … In a disinhibitory motif initially proposed theoretically 82 and …

… How these regions work together to subserve flexible … the distribution of triad motifs (graphs
made of three areas). … beyond local circuits toward a neuroscience of the whole brain. In …

… ability of the brain to hold and manipulate information when sensory stimulation is absent [
… of the brain. A working memory system is in turn conceptualized as a neural circuit endowed …

… how spatial navigation is integrated with escape to produce context-specific escape
requiring flexible decision-making to identify efficient flight routes in complex environments. …

… Here, we show that disinhibition provides a simple circuit motif … 2018), how disinhibition
functions in decision- making … nor predict contextual choice patterns (Wang, 2012) due to the lack …

… The brain is organized with a delicate structure to integrate and process both spatial and …
by strongly recurrent circuit dynamics to enhance signal propagation or routing of information is …

… The model predicted an efficient route through the MD for … of thalamic nuclei in the human
brain are suspected, evidence … of OFC in the network switching motif (dlPFC, OFC and MD), …

… Third, our results suggest a disinhibitory brain pathway onto both nodes of the core circuit, …
when our circuit model comprised a disinhibitory motif, not a quasi-equivalent excitatory motif, …

… A theme gaining prominence is therefore to understand pain … Only cells that express GFP,
Flp-DOG, and FLEX FRT -ChR2 (a … information processed in the S1 cortex gets routed through …

… if disinhibitory circuitry without strong I → I synapses was sufficient for flexible decision-…
By analyzing the connectivity structure of the model, we showed that a unique circuit motif that …