Best of 2016
The Best of JCEM 2016 highlights the outstanding progress of scientific research in endocrinology. A collection of the most highly rated peer reviewed articles of 2016, this compilation features important findings and notable advances encompassing the full range of clinical endocrine science and medicine.
Diabetes
Long-Term Improvement in Glucose Control and Counterregulation by Islet Transplantation for Type 1 Diabetes
Michael R. Rickels, Amy J. Peleckis, Eileen Markmann, Cornelia Dalton-Bakes, Stephanie M. Kong, Karen L. Teff, and Ali Naji
Published in November 2016
Metabolism/Obesity
A Common Variant and the Transcript Levels of MC4R Gene Are Associated With Adiposity in Children: The IDEFICS Study
Fabio Lauria, Alfonso Siani, Catalina Picó, Wolfgang Ahrens, Karin Bammann, Stefaan De Henauw, Ronja Foraita, Licia Iacoviello, Yiannis Kourides, Staffan Marild, Denes Molnar, Luis A. Moreno, Yannis Pitsiladis, Juana Sánchez, Toomas Veidebaum, Guan Wang, and Paola Russo, on behalf of the IDEFICS consortium
Published in November 2016
Adrenal Cortex/Hypertension
Serum RARRES2 Is a Prognostic Marker in Patients With Adrenocortical Carcinoma
Yi Liu-Chittenden, Dhaval Patel, Kelli Gaskins, Thomas J. Giordano, Guillaume Assie, Jerome Bertherat, and Electron Kebebew
Published in September 2016
Sexual and Gender-dependent Endocrinology
Testosterone Treatment and Sexual Function in Older Men With Low Testosterone Levels
Glenn R. Cunningham, Alisa J. Stephens-Shields, Raymond C. Rosen, Christina Wang, Shalender Bhasin, Alvin M. Matsumoto, J. Kellogg Parsons, Thomas M. Gill, Mark E. Molitch, John T. Farrar, David Cella, Elizabeth Barrett-Connor, Jane A. Cauley, Denise Cifelli, Jill P. Crandall, Kristine E. Ensrud, Laura Gallagher, Bret Zeldow, Cora E. Lewis, Marco Pahor, Ronald S. Swerdloff, Xiaoling Hou, Stephen Anton, Shehzad Basaria, Susan J. Diem, Vafa Tabatabaie, Susan S. Ellenberg, and Peter J. Snyder
Published in August 2016
Cross-Sex Hormone Treatment and Psychobiological Changes in Transsexual Persons: Two-Year Follow-Up Data
Alessandra D. Fisher, Giovanni Castellini, Jiska Ristori, Helen Casale, Emanuele Cassioli, Carolina Sensi, Egidia Fanni, Anna Maria Letizia Amato, Eva Bettini, Maddalena Mosconi, Davide Dèttore, Valdo Ricca, and Mario Maggi
Published in November 2016
Cardiovascular Endocrinology/Lipids
Ezetimibe-Simvastatin Therapy Reduce Recurrent Ischemic Stroke Risks in Type 2 Diabetic Patients
Chi-Hung Liu, Tien-Hsing Chen, Ming-Shyan Lin, Ming-Jui Hung, Chang-Ming Chung, Wen-Jin Cherng, Tsong-Hai Lee, and Yu-Sheng Lin
Published in August 2016
Growth, Growth Hormone, and Growth Factor
Randomized Trial of Aromatase Inhibitors, Growth Hormone, or Combination in Pubertal Boys with Idiopathic, Short Stature
Nelly Mauras, Judith L. Ross, Priscila Gagliardi, Y. Miles Yu, Jobayer Hossain, Joseph Permuy, Ligeia Damaso, Debbie Merinbaum, Ravinder J. Singh, Ximena Gaete, and Veronica Mericq
Published in December 2016
Endocrine Genetics
The Prevalence of GNAS Deficiency-Related Diseases in a Large Cohort of Patients Characterized by the EuroPHP Network
Francesca Marta Elli, Agnès Linglart, Intza Garin, Luisa de Sanctis, Paolo Bordogna, Virginie Grybek, Arrate Pereda, Federica Giachero, Elisa Verrua, Patrick Hanna, Giovanna Mantovani, and Guiomar Perez de Nanclares
Published in October 2016
Thyroid
IL-17A Exacerbates Fibrosis by Promoting the Proinflammatory and Profibrotic Function of Orbital Fibroblasts in TAO
Sijie Fang, Yazhuo Huang, Shuaiwei Wang, Yidan Zhang, Xuerui Luo, Luyan Liu, Sisi Zhong, Xingtong Liu, Dan Li, Rui Liang, Piccioni Miranda, Ping Gu, Huifang Zhou, Xianqun Fan, and Bin Li
Published in August 2016
Papillary Thyroid Carcinoma With Rare Exon 15 BRAF Mutation Has Indolent Behavior: A Single-Institution Experience
Liborio Torregrossa, David Viola, Elisa Sensi, Mirella Giordano, Paolo Piaggi, Cristina Romei, Gabriele Materazzi, Paolo Miccoli, Rossella Elisei, and Fulvio Basolo
Published in November 2016
Bone/Mineral Metabolism
Asfotase Alfa Treatment Improves Survival for Perinatal and Infantile Hypophosphatasia
Michael P. Whyte, Cheryl Rockman-Greenberg, Keiichi Ozono, Richard Riese, Scott Moseley, Agustin Melian, David D. Thompson, Nicholas Bishop, and Christine Hofmann
Published in January 2016
Hypothalamus/Pituitary
Effectiveness of Metyrapone in Treating Cushing’s Syndrome: A Retrospective Multicenter Study in 195 Patients
Eleni Daniel, Simon Aylwin, Omar Mustafa, Steve Ball, Atif Munir, Kristien Boelaert, Vasileios Chortis, Daniel J. Cuthbertson, Christina Daousi, Surya P. Rajeev, Julian Davis, Kelly Cheer, William Drake, Kirun Gunganah, Ashley Grossman, Mark Gurnell, Andrew S. Powlson, Niki Karavitaki, Isabel Huguet, Tara Kearney, Kumar Mohit, Karim Meeran, Neil Hill, Aled Rees, Andrew J. Lansdown, Peter J. Trainer, Anna-Elisabeth H. Minder, and John Newell-Price
Published in November 2016